When planning a trip to Colombia, chances are two cities will dominate your shortlist: Cartagena and Medellín. Both are iconic in their own right, yet they offer dramatically different experiences. Cartagena is a sun-soaked colonial city on the Caribbean coast, with cobbled streets, salsa music floating through the air, and unforgettable sunsets over ancient city walls.
Medellín, nestled in the Andes, tells a story of transformation: once troubled, now thriving and modern, full of art, innovation, and energy.
So, how do you decide where to base yourself? The choice isn’t just about where to sleep, it’s about the kind of journey you want. Do you dream of island escapes and balmy nights by the sea, or do you crave urban culture, cool weather, and mountain views?
Let’s dive into the differences to help you choose the perfect base for your Colombia adventure.
Vibe and Atmosphere
Cartagena feels like a living painting. The old walled city is a UNESCO World Heritage Site, filled with vivid colors, colonial architecture, and a slow, sultry rhythm. It’s romantic and full of character, ideal for travelers who want to soak in history and tropical charm.
Medellín couldn’t be more different in tone. Known as the “City of Eternal Spring,” it’s got a year-round mild climate, a booming tech scene, and a youthful buzz. Street art, rooftop bars, and innovative public spaces give Medellín a modern, forward-looking feel.
Getting There and Around
Both cities are well-connected internationally, but logistics can play a role in your decision. Cartagena’s airport is close to the city center, which means quicker arrivals and departures. Medellín’s José María Córdova International Airport is a bit farther out, but it tends to offer more international flight options and smoother infrastructure overall.
Before locking in flights, be sure to double-check the Colombia entry requirements for your nationality. While most travelers can enter visa-free or with an easy e-visa, entry policies can vary slightly depending on your country of origin.
Knowing the latest requirements in advance will save you time and potential hassle at the airport, no matter which city you choose to fly into.
Things to Do
If you’re looking for beach days, Cartagena takes the lead. It’s the gateway to islands like Barú and the Rosario Archipelago, perfect for day trips or overnight stays. The historic district is also great for walking tours, local cuisine, and people-watching in the plazas.
Medellín leans more toward cultural immersion and adventure. Visit Comuna 13 for its story of resilience told through murals, take the Metrocable for sweeping views of the city, or venture out to nearby towns like Guatapé.
Budget and Lifestyle
Cartagena tends to be more expensive, especially in tourist-heavy areas. High-end hotels and beachfront restaurants come with a premium price tag. That said, there are affordable options if you know where to look, but expect your daily costs to be higher here overall.
Medellín is one of the most budget-friendly cities in Latin America, especially for long stays. Whether you’re a digital nomad or a backpacker, you’ll find great value in accommodation, food, and transport. The city has embraced a remote work culture, with dozens of coworking spaces and thriving expat communities.
At the end of the day, both Cartagena and Medellín offer something incredible. If your idea of the perfect base includes warm beaches, colonial beauty, and a slower pace, Cartagena is calling your name.
If you want to dive into city life, explore the mountains, and experience Colombia’s modern heartbeat, Medellín might be your match.
Either way, you can’t go wrong; you’re about to explore one of the most diverse and exciting countries in South America.
